4oz Tussionex (hydrocodone/chlorpheniramine)
4 oz Tussionex® (Hydrocodone / Chlorpheniramine) Oral Suspension
Tussionex® is a prescription-only extended-release cough and cold medication used to relieve severe cough and upper respiratory symptoms associated with allergies or the common cold. It combines an opioid cough suppressant with an antihistamine to provide long-lasting symptom control.
This formulation is designed to deliver 12-hour relief, helping patients manage persistent cough, runny nose, and sneezing when other treatments are ineffective.
Important: Tussionex contains hydrocodone, an opioid medication with a risk of dependence, misuse, and respiratory depression. Use only under medical supervision.
Key Medication Details
-
Medication Name: Tussionex® Pennkinetic® Extended-Release Suspension
-
Active Ingredients:
-
Hydrocodone polistirex (opioid antitussive)
-
Chlorpheniramine polistirex (antihistamine)
-
-
Dosage Form: Oral extended-release suspension
-
Bottle Size: 4 oz (118 mL)
-
Duration of Action: Up to 12 hours
-
Prescription Status: Rx only (controlled substance)
What Tussionex Is Used For
Tussionex is prescribed to help relieve:
-
Severe or persistent cough
-
Allergy-related cough symptoms
-
Runny nose and sneezing
-
Upper respiratory irritation
-
Cold-related nighttime coughing
It is typically recommended only when non-opioid cough medicines are ineffective.
How Tussionex Works
-
Hydrocodone suppresses the cough reflex in the brain, reducing the urge to cough
-
Chlorpheniramine blocks histamine to relieve allergy symptoms such as sneezing and runny nose
-
The extended-release formula allows fewer doses per day
Common Side Effects
-
Drowsiness or sedation
-
Dizziness
-
Nausea or vomiting
-
Constipation
-
Dry mouth or throat
Serious Risks & Warnings
-
Respiratory depression
-
Opioid dependence or misuse
-
Severe allergic reactions
-
Low blood pressure
-
Interaction with alcohol or sedatives
Seek immediate medical attention if breathing slows, confusion occurs, or severe drowsiness develops.
Important Safety Information
-
Use exactly as prescribed
-
Do not combine with alcohol, benzodiazepines, or other opioids
-
Do not drive or operate machinery while taking this medication
-
Keep out of reach of children
-
Not recommended for children unless explicitly prescribed
Storage Instructions
-
Store at room temperature
-
Protect from light
-
Keep tightly closed
-
Do not freeze
FAQ
What is Tussionex used for?
Tussionex is used to treat severe cough and allergy-related respiratory symptoms when other medications do not provide relief.
Is Tussionex a narcotic?
Yes. Tussionex contains hydrocodone, which is an opioid narcotic cough suppressant.
How long does Tussionex last?
Tussionex is an extended-release medication designed to last up to 12 hours per dose.
Can Tussionex cause drowsiness?
Yes. Drowsiness is common due to both hydrocodone and chlorpheniramine.
Is Tussionex addictive?
Yes. Because it contains hydrocodone, Tussionex has a risk of dependence and misuse if not taken as directed.
Can I take Tussionex with alcohol?
No. Combining Tussionex with alcohol can cause dangerous breathing problems and should be avoided.
Is Tussionex still prescribed?
Yes, but it is prescribed carefully and selectively due to opioid safety concerns.
Can Tussionex be used for long-term cough?
No. It is intended for short-term use only unless otherwise directed by a healthcare provider.
What should I do if I miss a dose?
Take it only if needed and never double doses. Follow your doctor’s instructions.
Is a prescription required for Tussionex?
Yes. Tussionex is a Schedule II/III controlled medication (classification may vary by country) and requires a valid prescription.
Who should not take Tussionex?
People with breathing disorders, opioid sensitivity, history of substance misuse, or those taking sedatives should avoid it unless advised by a doctor.
