Humira (Adalimumab) Medication
Humira (Adalimumab) Injection
About Humira (Adalimumab)
Humira® (adalimumab) is a prescription biologic medication used to treat a range of chronic autoimmune and inflammatory conditions. It works by blocking tumor necrosis factor-alpha (TNF-α), a protein in the immune system that causes inflammation, pain, and tissue damage.
Humira is widely prescribed for adults and children with moderate to severe inflammatory diseases when other treatments have not provided enough relief. It helps reduce symptoms, slow disease progression, and improve overall quality of life.
What Is Humira Used For?
Humira is FDA-approved to treat:
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Rheumatoid arthritis (RA) – moderate to severe
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Psoriatic arthritis (PsA)
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Ankylosing spondylitis
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Crohn’s disease
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Ulcerative colitis
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Polyarticular juvenile idiopathic arthritis (JIA) in children and adolescents
By targeting the root cause of inflammation, Humira helps reduce joint damage, relieve pain, and maintain remission in inflammatory bowel disease.
Humira Dosage & Administration
Medication Name: Humira®
Generic Name: Adalimumab
Dosage Forms:
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Pre-filled syringe
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Pre-filled pen
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Vial
Available Strengths:
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40 mg/0.8 mL
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80 mg/0.8 mL
Dosage Frequency:
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Every other week (most common)
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Weekly (for certain conditions)
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Monthly (in specific cases)
Route of Administration:
Subcutaneous injection (under the skin)
Humira is usually injected into the thigh or abdomen. Your healthcare provider will determine the exact dosing schedule based on your condition and response.
Common Side Effects of Humira
Most side effects are mild to moderate and may improve over time:
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Injection site reactions (redness, swelling, pain)
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Cold-like symptoms (runny nose, sore throat, cough)
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Headache
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Fatigue
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Nausea
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Abdominal pain
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Skin rash
Serious Side Effects (Rare but Important)
Humira can weaken the immune system and may cause serious side effects, including:
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Serious or life-threatening infections
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Severe allergic reactions
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Liver problems
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Heart failure
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Neurological disorders
Seek medical attention immediately if you experience fever, shortness of breath, chest pain, severe weakness, or unusual bruising.
Important Safety Information
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Humira is a prescription-only medication
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Tell your doctor about all medical conditions and medications
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Avoid close contact with people who are sick
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Do not receive live vaccines while taking Humira
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Regular blood tests may be required
Storage Instructions
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Store in the refrigerator at 36°F to 46°F (2°C to 8°C)
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Do not freeze
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Can be stored at room temperature for up to 30 days
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Once removed from the fridge, do not return it
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Discard if frozen or kept at room temperature longer than 30 days
Missed Dose Instructions
If you miss a dose:
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Take it as soon as you remember
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If it’s close to your next dose, skip the missed dose
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Do not double your dose
Drug Interactions
Humira may interact with:
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Methotrexate
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Azathioprine
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Mercaptopurine
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Leflunomide
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Sulfasalazine
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Abatacept
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Anakinra
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Tocilizumab
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Rituximab
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Cyclosporine
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Tacrolimus
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Natalizumab
Always inform your healthcare provider of all medications you take.
FAQ
What are the worst side effects of Humira?
The most serious risks include severe infections, liver problems, heart failure, and rare neurological conditions. These are uncommon but require immediate medical care.
Is Humira worth the risks?
For many patients with severe autoimmune diseases, Humira significantly improves symptoms and quality of life. Your doctor will assess whether the benefits outweigh the risks for your condition.
What should you avoid while taking Humira?
Avoid live vaccines, exposure to infections, and starting new medications without consulting your doctor.
What organ does Humira affect most?
Humira primarily affects the immune system, but it can also impact the liver, nervous system, and heart in rare cases.
How much does Humira cost?
Humira is a high-cost biologic medication. Prices vary based on dosage, location, insurance, and availability of biosimilars such as adalimumab-adaz.
Is adalimumab-adaz the same as Humira?
Adalimumab-adaz is a biosimilar to Humira. It is highly similar in safety and effectiveness but may be more affordable.
Can Humira cure autoimmune diseases?
No. Humira helps control symptoms and inflammation, but it does not cure autoimmune conditions.
How long does Humira take to work?
Some patients notice improvement within 2–4 weeks, but full benefits may take several months.
