LL-37 Peptide (5mg) – Research Grade
LL-37 Peptide (5mg) is a research-grade synthetic antimicrobial peptide derived from the C-terminal region of the human cathelicidin protein hCAP-18. Composed of 37 amino acids, LL-37 is the only known human cathelicidin peptide and is extensively studied in innate immunity, antimicrobial defense, inflammation, wound healing, epithelial biology, and immunomodulatory signaling.
Researchers use LL-37 in preclinical and in vitro studies investigating host defense mechanisms, microbial membrane interactions, immune cell recruitment, tissue repair, and inflammatory pathway regulation. Its broad-spectrum antimicrobial activity and multifunctional biological properties have made LL-37 one of the most widely investigated peptides in innate immune research.
For Research Use Only. Not for human use.
For Research Use Only. Not for human use.
LL-37 Peptide Research Overview
LL-37 is produced through the proteolytic cleavage of the human cathelicidin precursor protein hCAP-18. Under physiological conditions, LL-37 adopts an α-helical structure that enables interactions with microbial membranes and host immune receptors.
Because of its diverse biological functions, LL-37 is widely studied in laboratory models involving:
- Innate immune responses
- Antimicrobial peptide research
- Host-pathogen interactions
- Inflammatory signaling
- Wound healing biology
- Chemotaxis
- Epithelial barrier function
- Cell migration
- Tissue regeneration
- Drug discovery
All research involving LL-37 should be conducted under validated institutional laboratory protocols.
Product Specifications
| Specification | Details |
|---|---|
| Product | LL-37 Peptide |
| Strength | 5 mg |
| Peptide Type | Human Cathelicidin Antimicrobial Peptide |
| Sequence | Leu-Leu-Gly-Asp-Phe-Phe-Arg-Lys-Ser-Lys-Glu-Lys-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser |
| Molecular Formula | C205H340N60O53 |
| Molecular Weight | 4493 g/mol |
| CAS Number | 154947-66-7 |
| PubChem CID | 16198951 |
| Synonyms | CAP-18, Cathelicidin, Antibacterial Peptide LL-37, Ropocamptide |
| Appearance | Lyophilized Powder |
| Grade | Research Grade |
| Purity | ≥99% (HPLC Verified) |
| Quality Testing | HPLC, LC-MS, COA Available |
| Intended Use | Laboratory Research Only |
Research Applications
LL-37 Peptide is commonly investigated in laboratory research involving:
- Innate immunity
- Antimicrobial mechanisms
- Host-pathogen interactions
- Bacterial membrane disruption
- Immunomodulation
- Cytokine signaling
- Wound healing biology
- Chemotaxis
- Epithelial regeneration
- Drug discovery
LL-37 is not approved for clinical, therapeutic, veterinary, or diagnostic applications.
LL-37 Peptide Benefits
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Within laboratory research, LL-37 has attracted significant attention because of its broad biological functions.
Published preclinical studies have investigated LL-37 in relation to:
- Broad-spectrum antimicrobial activity
- Innate immune defense
- Immunomodulatory signaling
- Cytokine regulation
- Chemotactic activity
- Wound healing mechanisms
- Epithelial cell migration
- Tissue regeneration
- Biofilm research
- Host defense peptide biology
These findings are limited to laboratory and preclinical research and should not be interpreted as evidence of clinical safety or effectiveness.
LL 37 Peptide 5mg Benefits
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The 5 mg presentation is commonly selected for pilot studies, assay development, and mechanistic laboratory investigations.
Researchers utilize LL-37 (5 mg) for:
- Cell culture experiments
- Antimicrobial pathway research
- Immunology studies
- Host defense investigations
- Chemotaxis assays
- Inflammation models
- Tissue repair research
- Drug discovery screening
This material is intended exclusively for scientific investigation.
LL 37 Peptide 5mg Price
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The price of LL-37 Peptide (5 mg) depends on several factors, including:
- Research-grade purity
- Third-party analytical testing
- Manufacturing standards
- Batch quality
- Certificate of Analysis (COA)
- Inventory availability
Current pricing is available on the product page.
LL 37 Peptide 5mg Dosage
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Because LL-37 is not approved for human or veterinary use, there is no established therapeutic dosage.
Research concentrations are selected according to:
- Experimental design
- Cell type
- Published literature
- Assay methodology
- Laboratory SOPs
- Detection chemistry
Each laboratory should independently validate concentrations appropriate for its research.
LL-37 Peptide Dosage Per Day
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There is no approved daily dosage for LL-37 because this product is not intended for human administration.
Experimental concentrations vary depending upon:
- Cell culture models
- Animal research models
- Assay objectives
- Experimental duration
- Detection methods
LL 37 Peptide 5mg Side Effects
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Since LL-37 Peptide is supplied solely for laboratory research, there is no established clinical safety profile or approved side-effect information for human use.
Researchers should follow all institutional laboratory safety procedures, including:
- Appropriate PPE
- Safe peptide handling
- Accurate documentation
- Proper storage
- Controlled reconstitution
LL-37 is not intended for human consumption.
LL 37 Peptide 5mg For Sale
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Research laboratories purchasing LL-37 typically prioritize:
- ≥99% peptide purity
- Independent analytical verification
- Certificate of Analysis (COA)
- Batch consistency
- Secure packaging
- Research-grade manufacturing
- Reliable documentation
Every batch is manufactured for laboratory research applications only.
LL-37 Peptide Buy
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When buying LL-37 for research purposes, laboratories often evaluate:
- HPLC purity testing
- LC-MS identity confirmation
- COA availability
- Research-grade manufacturing
- Batch traceability
- Secure shipping
- Quality assurance documentation
Selecting a research-grade supplier helps improve reproducibility across preclinical studies.
Laboratory Handling
Receiving
Upon receiving LL-37 Peptide:
- Verify product identity.
- Confirm lot numbers.
- Inspect packaging integrity.
- Compare shipment documentation.
- Retain packaging until verification is complete.
Reconstitution
Researchers should:
- Follow institutional SOPs.
- Validate solvent compatibility.
- Record lot numbers before reconstitution.
- Prepare assay buffers before opening the vial.
- Clearly label aliquots.
- Minimize freeze-thaw cycles.
Storage
To preserve peptide integrity:
- Store sealed in the original vial.
- Protect from moisture, humidity, and direct light.
- Maintain long-term storage at -4°F (-20°C) or colder.
- Refrigerate at approximately 39°F (4°C) for short-term laboratory use.
- Avoid repeated freeze-thaw cycles whenever possible.
Lyophilized LL-37 contains no fillers, helping preserve peptide purity and stability throughout storage.
Quality Assurance
Every batch of LL-37 Peptide is supported by independent quality verification.
Third-party analytical testing typically includes:
- High-Performance Liquid Chromatography (HPLC) purity testing (typically ≥99%)
- Liquid Chromatography-Mass Spectrometry (LC-MS) identity confirmation
- Molecular weight verification
- Chemical contaminant screening
- Residual solvent analysis
- Sterility and endotoxin testing where applicable
Each batch is accompanied by or linked to a Certificate of Analysis (COA), enabling researchers to verify molecular identity and quality before use.
Why Researchers Choose LL-37 Peptide
Research laboratories frequently select LL-37 because it offers:
- Research-grade purity
- Third-party analytical testing
- COA documentation
- Consistent manufacturing standards
- Reliable batch traceability
- Suitability for antimicrobial and immunology research
- Compatibility with wound healing and inflammation studies
- Support for mechanistic pathway investigations
Frequently Asked Questions
What is LL-37 Peptide?
LL-37 is a synthetic form of the human antimicrobial peptide derived from the C-terminal region of the cathelicidin protein hCAP-18. It is widely studied for its role in innate immunity, antimicrobial defense, immunomodulation, and tissue repair.
What are the benefits of LL-37 peptide?
In laboratory research, LL-37 has been investigated for its potential role in antimicrobial activity, immune regulation, chemotaxis, epithelial repair, wound healing, and inflammatory signaling. These observations are limited to preclinical studies and should not be interpreted as clinical benefits.
What is LL-37 used for in research?
Researchers commonly investigate LL-37 in:
- Antimicrobial peptide biology
- Host-pathogen interactions
- Innate immune responses
- Wound healing models
- Chemotaxis studies
- Cytokine signaling
- Epithelial regeneration
- Drug discovery
- Biofilm research
Is LL-37 FDA approved?
No. LL-37 has not been approved by the U.S. Food and Drug Administration (FDA) for any therapeutic, diagnostic, or medical application.
Is LL-37 intended for human use?
No. LL-37 Peptide is supplied strictly for research purposes only and is not intended for human or veterinary use.
How is LL-37 supplied?
LL-37 is supplied as a lyophilized (freeze-dried) research peptide powder that contains no fillers, helping preserve purity and stability during storage.
What vial size is available?
This product is supplied as:
- LL-37 Peptide (5 mg)
How should LL-37 be stored?
For maximum stability:
- Store sealed at -4°F (-20°C) or colder.
- Protect from light and humidity.
- Refrigerate at approximately 39°F (4°C) for short-term storage.
- Avoid repeated freeze-thaw cycles.
Research Use Disclaimer
For Research Use Only. Not for human use.
LL-37 Peptide (5 mg) is supplied exclusively as a research-grade laboratory compound for qualified scientific investigation. It is not intended for human or veterinary use and must not be used to diagnose, treat, cure, or prevent any disease. This product has not been evaluated or approved by the U.S. Food and Drug Administration (FDA) for therapeutic or clinical applications.
